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7. June 2025🧬 What is Dapoxetine? Effects, uses and safety
Dapoxetine is the first approved drug designed specifically to treat premature ejaculation (PE) in men. It belongs to the group of SSRIs (selective serotonin reuptake inhibitors), but unlike conventional antidepressants, it has a rapid onset of action and a short half-life, which allows it to be taken once before sexual activity.
It is mainly known under the Priligy brand, which is available in many countries, including the Czech Republic and Slovakia.
🔬 How does Dapoxetine work?
Premature ejaculation is often associated with low serotonin levels in the brain. Dapoxetine increases serotonin levels in nerve connections and thus slows down the ejaculatory reflex.
In this way, it can extend the time to semen ejaculation up to 2-3 times compared to normal, thus improving a man’s sexual stamina and self-confidence.
💊 Dosage and method of use
Dapoxetine is taken only on demand, not every day. The recommended dosage is:
- 60 mg about 1 to 3 hours before planned sexual intercourse
- For some men, a lower dose of 30 mg may be sufficient
- The tablet is taken with a full glass of water
- Not recommended to combine with alcohol
Maximum frequency of use: 1 tablet per 24 hours
✅ Benefits of Dapoxetine
- The only officially approved drug for premature ejaculation
- Fast onset of action (within 1 hour)
- The effect lasts for several hours
- Easy dosing “on demand”
- Possibility of combination with erectile dysfunction drugs (after consultation with a doctor)
⚠️ Side effects
Dapoxetine is generally well tolerated, but it can cause:
- Nausea (the most common side effect)
- Dizziness
- Headache
- Diarrhea
- Sleeplessness
More serious but rare side effects:
- Syncope (sudden short-term loss of consciousness)
- Drop in blood pressure
- Mood swings
To avoid side effects, it is important not to increase the dose without the advice of a doctor and to avoid driving or operating machines after use.
❗ When not to take dapoxetine?
Dapoxetine is not suitable for:
- Men under 18 or over 65 years of age
- Men with severe heart, liver, or kidney disease
- While taking other SSRIs or MAOIs (depression medications)
- Low blood pressure or epilepsy
Alcohol increases the risk of dizziness and fainting, so it is not recommended to combine it with dapoxetine.
💬 The most famous brands of dapoxetine
Title | Active ingredient | Available dosages | Country of availability |
---|---|---|---|
Priligy | Dapoxetine | 30mg, 60mg | Czech Republic, Slovakia, EU |
Dapoxetine Sandoz | Dapoxetine | 30mg, 60mg | Generic available in the EU |
Poxet | Dapoxetine | 30mg, 60mg | India (over-the-counter online)* |
*Note: Poxet and other generics from unofficial sources may not be approved and safe. Always prefer a certified supplier or pharmacy.
🤔 Possible combination with erection drugs
Dapoxetine can be combined with erectile dysfunction drugs (e.g. sildenafil, tadalafil) if a man has erection problems and premature ejaculation at the same time.
This combination is common, but must be supervised by a doctor, as both types of medications can affect pressure and neurological responses.
✅ Summary
Dapoxetine (e.g. Priligy) represents a modern and effective solution for men who suffer from premature ejaculation. Thanks to its fast action, simple dosage and relatively good tolerability, it is an ideal choice for single use. It helps to extend the duration of intercourse and improve the sexual satisfaction of both partners.
As always, it is recommended to consult your condition with a doctor before starting to start treatment.